Results 41 to 50 of about 323,693 (310)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Experimental study on the effect of partial shear studs layout on flexural behavior of steel-concrete composite beams

open access: yesResults in Engineering
In steel-concrete composite beams, partial shear connection offers advantages including greater ductility and lower cost. However, partial shear connection constraints on composite beam structural performance, such as reduced beam stiffness, increased ...
Amanyire Barozi Victoire   +2 more
doaj   +1 more source

Inelastic Strength for Fire Resistance of Composite I-Beam Covered by Insulation Material Subjected to Basic Loading Condition

open access: yesMetals, 2021
This paper presents a nonlinear numerical study on the moment resistance of composite steel-concrete beam using fire insulation subjected to various fire scenarios and basic loading conditions.
Xuan Tung Nguyen, Jong Sup Park
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Partially connected composite beams [PDF]

open access: yesPAMM, 2006
AbstractAnalytical solutions to some boundary value problems for a steel‐concrete composite beam with deformable shear connectors in the elastic range are presented. The obtained results show that the distribution of slip on the bond interface between the concrete slab and the steel girder is not a monotone function, even in the case of uniform loading
Mieczysław Kuczma, Bożena Kuczma
openaire   +1 more source

Finite element formulation for free vibration of composite beams [PDF]

open access: yes, 2008
Investigations concerning the dynamic response of composite beams with partial interaction are scarce. Derivation of the differential equations describing the interaction between composite elements normally involves with the solution of high order system
Mohd. Haniffah, Mohd. Ridza
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Dynamical analysis of machining tool body with reinforced inner core of circular shape [PDF]

open access: yesApplied and Computational Mechanics, 2009
The vibration analysis of a clamped beam structure representing vibrating machining body tool is solved in this paper. The required modal properties of beam are obtained by application the reinforcing core with circular cross section.
Naď M.
doaj  

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