Results 191 to 200 of about 2,341 (249)

Valorization of Onion By-Products and Assessment of Their Biological Activities. [PDF]

Foods
Rabie M, Khazaal S, Othman MM, Salem Sokhn E, Debs E, Sunoqrot S, Azakir B, Louka N, El Darra N.   +8 more
europepmc   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

3D analysis of smile transformation in patients with class III deformities following orthognathic surgery: a stereophotogrammetric study : Original Article. [PDF]

Clin Oral Investig
Enez A, Altıparmak N, Akdeniz BS, Akdeniz SS.   +3 more
europepmc   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Predicting pregnancy-related low back pain: a prospective cohort protocol integrating motor control and functional movement tests with pressure pain thresholds. [PDF]

BMC Pregnancy Childbirth
Ghaffari R, Bahramnaghd M, Hosseinzadeh M.   +2 more
europepmc   +1 more source

Ferroptosis Suppression by the M6A Reader IGF2BP1 Underlies Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu, Yue Huang, Jing‐Yuan Ye, Si‐Yuan Lu, Zhi‐De Liu, Ming‐Jian Ma, De‐Liang Fang, Zi‐Yi Zhao, Jin‐Zhao Xie, Jiao Chen, Xiao‐Yu Yin   +10 more
wiley   +1 more source

Vibrissae-inspired vision-based magnetic-actuated whisker. [PDF]

Nat Commun
Hu Z, Cheng Y, Wachs J, She Y.
europepmc   +1 more source

Trueness and precision of facial scan and virtual patient representation workflow. [PDF]

J Prosthodont
Al Hamad KQ, Ayyad JQ, Al-Rashdan BA, Al Quran FA.   +3 more
europepmc   +1 more source

Direct Samples of Interstellar and Interplanetary Material with IMAP. [PDF]

Space Sci Rev
Szalay JR, Provornikova E, Ayari E, Bzowski M, Christian ER, Funsten HO, Galli A, Gkioulidou M, Horányi M, Livi S, McComas DJ, Möbius E, Ogasawara K, Rahmanifard F, Rankin JS, Reisenfeld DB, Schwadron NA, Sternovsky Z, Swaczyna P, Turner D, Zank GP, Zirnstein EJ.   +21 more
europepmc   +1 more source

Explainable judgment prediction and article-violation analysis using deep LexFaith hierarchical BERT model. [PDF]

Sci Rep
Zhang X, Liu S.
europepmc   +1 more source