Results 41 to 50 of about 99,383 (266)

Experimental research on fire resistance of circular steel tube column filled with steel-reinforced high-strength concrete

open access: yes上海师范大学学报. 自然科学版, 2014
Circular steel tube filled with steel-reinforced high-strength concrete is a new model of composite column design.The fire resistance of this composite column was investigated experimentally.One circular steel tube column filled with steel-reinforced ...
ZHU Siyi   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Numerical Analysis and Resistance Design of UHPC- and UHTCC-Encased Rectangular Steel Tubular Columns Subject to Axial Compression

open access: yesBuildings
Ultra-high performance concrete (UHPC) and ultra-high toughness cementitious composite (UHTCC) offer superior mechanical properties compared to normal concrete, with UHPC excelling in compressive strength and UHTCC in tensile ductility and crack ...
Xiao-Yang Min   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Buckling of Slender Concrete-Filled Steel Tubes with Compliant Interfaces

open access: yesLatin American Journal of Solids and Structures
This paper presents an exact model for studying the global buckling of concrete-filled steel tubular (CFST) columns with compliant interfaces between the concrete core and steel tube.
Simon Schnabl, Igor Planinc
doaj   +1 more source

Compressive Behavior of Composite Concrete Columns with Encased FRP Confined Concrete Cores

open access: yesSensors, 2019
A composite concrete column with encased fiber reinforced polymer (FRP) confined concrete cores (EFCCC) is proposed in this paper. The cross-sectional form of the EFCCC column is composed of several orderly arranged FRP confined concrete cores (FCCCs ...
Xuxu Wang   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Numerical study of concrete-filled steel composite (CFSC) stub columns with steel stiffeners

open access: yesLatin American Journal of Solids and Structures
Numerical study of concrete-filled steel composite (CFSC) stub columns with steel stiffeners is presented in this paper. The behaviour of the columns is examined by the use of the finite element software LUSAS.
Alireza Bahrami   +2 more
doaj   +1 more source

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