Results 51 to 60 of about 5,362,251 (232)

Correlation analysis of dietary inflammatory index and composite dietary antioxidant index with sex hormone levels in children and adolescents

Guangxi Yike Daxue xuebao
Objective To explore the correlation of the dietary inflammatory index (DII) and composite dietary antioxidant index (CDAI) with sex hormone levels in children and adolescents. Methods A cross-sectional analysis was conducted using data from the National
Suyan ZHOU, Shun LIU, Fengxiang QIN
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Association between the composite dietary antioxidant index and all-cause mortality in individuals with osteoarthritis via NHANES data

Scientific Reports
The impact of antioxidant intake on the prognosis of osteoarthritis (OA) patients remains unclear. The aim of this study was to investigate the relationship between the composite dietary antioxidant index (CDAI) and all-cause mortality in OA patients.
Wei Jiang, Jie Li, Haopeng Li
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity [PDF]

, 2010
Background Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype “waist circumference for a given body mass index (WCBMI)”, a proxy measure of visceral adiposity, is deemed necessary ...
Feskens, EJM, Masala, G, A, D.L., van der, Sorensen, T., Boeing, H, Palli, D, Sorensen, TIA, Wareham, N., Riboli, E., Halkjaer, J, Romaguera, D., Forouhi, N.G., Overvad, K, Jakobsen, M.U., Riboli, E, Huaidong, D.U., Jakobsen, MU, Palli, D., Masala, G., Aengquist, L, Angquist, L., Tjonneland, A, Boeing, H., Steffen, A., Overvad, K., van der A, DL, Feskens, E.J.M., Steffen, A, Halkjaer, J., Du, H, Forouhi, NG, Wareham, NJ, Romaguera, D, van der A, D.L., Tjonneland, A.   +34 more
core   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Relationship between Composite Dietary Antioxidant Index and Aging

, 2023
Background: Numerous studies have demonstrated a close relationship between antioxidant-rich diets and comorbidities as well as mortality. However, the relationship between such diets and aging remains unclear.
Haiting Wang, Yongbing Chen
core   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

The triglyceride-glucose index mediates associations between dietary inflammation index/Composite Dietary Antioxidant Index and cardiovascular disease incidence: insights from NHANES study

Experimental Gerontology
Aims: This study investigates how Dietary Inflammatory Index (DII) and Composite Dietary Antioxidant Index (CDAI) patterns relate to cardiovascular disease, with particular focus on their metabolic connections, providing novel insights for prophylaxis ...
Han Gao, Bo Yan, Fangyuan Cheng, Shishuang Zhang, Pan Liao, Dai Li, Lin Zhang, Fanglian Chen, Ping Lei   +8 more
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source