Results 101 to 110 of about 288,253 (317)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Analysis of thick laminated composite plates on an elastic foundation with the use of various plate theories

open access: yes, 2005
In this study, various theories of composite laminated plates are extended to rectangular composite laminates resting on an elastic foundation. First, an analysis based on the classical theory of laminated plates is employed.
Akavci S.S.
core   +1 more source

Elastic Foundation Constants for Sandwich Composites

open access: yesAIAA Journal, 2018
Elastic foundation models are often used in fracture mechanics applied to face/core debonds in sandwich composites or in face wrinkling studies. The elastic constants to be used in these models are the most important element in these formulations.
George A. Kardomateas   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Experimental Comparison Study on Behavior of Combined Piles Composite Foundation

open access: yes, 2011
The combined pile composite foundation has the advantages of good technical and economic effects, yet there are no mature analysis methods to practise in design and test at present.
De Quan Zhou, Hong Li Liu
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A generic analytical solution for creep and partial interaction in composite beams

open access: yes, 2004
This paper addresses the issue of creep deformations and the deformations caused by partial shear interaction in composite T-section beams. Partial interaction in composite beams was first modelled analytically in the seminal publication of Newmark ...
Ranzi, Gianluca   +2 more
core  

Behavior of composite pavement foundation materials subjected to cyclic loading

open access: yes, 2011
This study investigated relationships between field and laboratory moduli in relation to the pavement thickness design values and how individual foundation layers affect the composite moduli of pavement foundation systems.
Wolfe, Alexander
core   +1 more source

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