Results 171 to 180 of about 549,019 (312)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Investigation of the Possibilities of Regulating Boundary Processes in the Composite Material Made from Scrap Tires and Polymer Binder

open access: yes
Investigation of the possibility to regulate the boundary processes in the composite material made from scrap tires and polymer binder must be considered as a perspective direction so that to regulate the essential properties of composite material.
Mālers, Laimonis, Plēsuma, Renāte
core  

Development of a Finite Element Methodology for the Collapse Analysis of Composite Aerospace Structures

open access: yes, 2007
In this work, an analysis methodology for capturing the critical damage mechanisms leading to collapse in composite stiffened structures is proposed. One aspect of the methodology is a global-local analysis technique that monitors a strength criterion in
Thomson, Rodney   +2 more
core  

Toward Flexible and Wearable Zn–Air Batteries from Cotton Textile Waste

open access: yesACS Omega, 2019
Xingyang Huang   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Integrated Sensor-Composite Material Platform for High-Resolution Voltage Mapping in Tissue-Mimicking Models. [PDF]

open access: yesACS Omega
Jain KC   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Study on an Electrochemical Immunosensor for Sensitive Detection of Myoglobin Based on Graphene-Nanogold Composite Material. [PDF]

open access: yesACS Omega
Chen W   +11 more
europepmc   +1 more source

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