Results 151 to 160 of about 6,887,631 (298)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Non-linear analysis of multi-span composite beams under combined flexure and torsion

, 2015
Multi-span steel-concrete composite beams fabricated from two steel joists and one concrete slab are widely utilised in bridges and highway interchanges, and are commonly subjected to combined actions of flexure and torsion.
Uy, Brian, Tan, Ee Loon (R14425), Ban, Huiyong   +2 more
core  

Benzimidazole-Regulated 1D 4-Fluorosalicylic Acid MOF Composite Material Design and Its Application in Glucose Sensing. [PDF]

Molecules
Wu H, Yu D, Hu J, Wang F, Zhang S, Guo K, Pang H.   +6 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Toward Flexible and Wearable Zn–Air Batteries from Cotton Textile Waste

ACS Omega, 2019
Xingyang Huang, Jie Liu, Jia Ding, Yida Deng, Wenbin Hu, Cheng Zhong   +5 more
doaj   +1 more source

Optimization of Nanosecond Laser Polishing Process for TC4-B₄C Composite Material and Study on Surface Quality. [PDF]

Materials (Basel)
Zhang J, Yang Y, Zhu L, Xu W, Liu Z.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Study of the potential of composite material based on zeolite and geopolymer as an adsorbent of toxic metals. [PDF]

Environ Sci Pollut Res Int
da Silva Nascimento RJ, de Loiola IC, Sousa JVT, de Oliveira Sousa Neto V, da Silva LTV, do Nascimento RF.   +5 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Advancing biomedical innovation through composite material strategies. [PDF]

Biomater Transl
Chen S, Xia W, Li B.
europepmc   +1 more source