Results 141 to 150 of about 552,574 (312)
The Effects of fibre pre-stressing on the impact performance of composite laminates [PDF]
, 2011 This thesis has presented the results and findings of a study carried out into the effects of fibre pre-stressing on the impact performance of composite laminates.
Jevons, Matthew Paul
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Silkfibroin-Ca-P composite bone replacement material for guided bone growth [PDF]
, 2015 Mineralized natural protein based materials are investigated as novel materials to be used in tissue engineering and as bone replacement materials.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Shock and VibrationA method to deduce the characteristics of rail corrugation was developed and presented in this paper. It has been found that noise and vibration in the train vehicle were primarily contributed by rail corrugation and wheel polygonalisation.
Xiaohan Phrain Gu +3 more
doaj +1 more source
Investigation of the Possibilities of Regulating Boundary Processes in the Composite Material Made from Scrap Tires and Polymer Binder [PDF]
Investigation of the possibility to regulate the boundary processes in the composite material made from scrap tires and polymer binder must be considered as a perspective direction so that to regulate the essential properties of composite material.
Mālers, Laimonis, Plēsuma, Renāte
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Development of a Finite Element Methodology for the Collapse Analysis of Composite Aerospace Structures [PDF]
, 2007 In this work, an analysis methodology for capturing the critical damage mechanisms leading to collapse in composite stiffened structures is proposed. One aspect of the methodology is a global-local analysis technique that monitors a strength criterion in
Thomson, Rodney +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source