Results 121 to 130 of about 549,019 (312)

An integrated structural health monitoring approach to composite-based pipeline repair [PDF]

open access: yes, 2011
One of the most common problems in the structural integrity of industrial pipelines is external corrosion. Composite materials have been accepted as a repair option to restore the original strength of the effected damaged section but the approach to ...
Abd Murad, Mahadi
core  

The effect of graphene solution on mixed powder electrical discharge milling of Ti6Al4V

open access: yesMaterials Research Express
Ti6Al4V is the most widely used materials in aerospace, medical, nuclear power and other fields. However, due to its unique properties such as low thermal conductivity, titanium alloy poses challenges in machining processes. Electrical discharge milling (
Yuexiang Du   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Future Design for Composite Airframe Structures – The Projects POSICOSS and COCOMAT

open access: yes, 2006
European aircraft industry demands for reduced development and operating costs, by 20% and 50% in the short and long term, respectively. Contributions to this aim are provided by the completed project POSICOSS and the running follow-up project COCOMAT ...
Degenhardt, Richard
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Theoretical and numerical investigation on internal instability phenomena in composite materials

open access: yes, 2004
Instability phenomena occurring in the microstructure of composite materials are investigated. To this aim, a complete description of the mechanical behavior of bi-material interfaces in composite materials requires the definition of both a cohesive ...
Paggi, Marco, Carpinteri, Alberto
core  

A structural design comparison of metallic and composite aircraft pressure retaining doors [PDF]

open access: yes, 2012
The pressure retaining door is obviously a sensible part of an aircraft, and the design criteria is much more critical than for the fuselage, so a problem caused by this critical criteria is the heavy weight of the door structure because it should be ...
Liu, Hongfen
core  

Effect of current density on the microstructure and properties of supercritical Ni-FG composite electrodeposited layers

open access: yesJournal of Materials Research and Technology
This study investigates the surface morphology and microstructure of nickel (Ni) plating and nickel-fluorinated graphene (Ni-FG) composite plating, both produced using a direct current (DC) power supply under standard and supercritical conditions.
Haoyu Zhong   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Development of a Degradation Model for the Collapse Analysis of Composite Aerospace Structures

open access: yes, 2006
For stiffened structures in compression the most critical damage mechanism leading to structural collapse is delamination or adhesive disbonding between the skin and stiffener.
Adrian C. Orifici   +9 more
core  

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