Results 101 to 110 of about 549,019 (312)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Interaction curves for vibration and buckling of thin-walled composite box beams under axial loads and end moments

open access: yes, 2010
Interaction curves for vibration and buckling of thin-walled composite box beams with arbitrary lay-ups under constant axial loads and equal end moments are presented.
Lee, Jaehong, Vo, Thuc
core   +1 more source

Thermoelectric and Ignition Effects of Lightning Strikes on Composite–Metal Lap Joints

open access: yesAerospace
Carbon fiber-reinforced polymer (CFRP) composite–metal joint structures are susceptible to localized discharge and thermal damage under lightning current, posing serious safety concerns for critical aircraft components such as fuel tanks.
Kui Du   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A Composite Material Based on Recycled Tires

open access: yes
Present work is devoted to elaboration and investigation of composite material with defined properties based on mechanically grinded recycled tires and polymer binder.
Mālers, Laimonis   +2 more
core  

Imperfection investigation of composite stiffened fuselage panels for Postbuckling analyses

open access: yes, 2008
Project COCOMAT is an ongoing four year European Commission project aimed at exploiting the large reserve of strength in composite structures through more accurate prediction of collapse. As part of the research program, curved stiffened composite panels
Thomson, Rodney   +3 more
core  

Ballistic response mechanism and resistance-driven evaluation method of UHMWPE composite

open access: yesDefence Technology
The use of ultra-high molecular weight polyethylene (UHMWPE) composite in the design of lightweight protective equipment, has gained a lot of interest.
Yemao He   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Composite material and method for production of improved composite material

open access: yes, 1996
A laminated composite material with improved interlaminar strength and damage tolerance having short rods distributed evenly throughout the composite material perpendicular to the laminae.
Farley, Gary L.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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