Results 101 to 110 of about 6,887,631 (298)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Ballistic response mechanism and resistance-driven evaluation method of UHMWPE composite
Defence TechnologyThe use of ultra-high molecular weight polyethylene (UHMWPE) composite in the design of lightweight protective equipment, has gained a lot of interest.
Yemao He +5 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Effect of Moisture on the Material Properties of Composite Material
Nowadays, composite materials are widely used in the aeronautical industry to manufacture many different components. Development of composite materials has a very positive influence on the performance, reliability, weight and cost of modern aircraft. But
Kovaļovs, Andrejs +2 more
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Multilayer Electroactive Polymer Composite Material [PDF]
, 2011 An electroactive material comprises multiple layers of electroactive composite with each layer having unique dielectric, electrical and mechanical properties that define an electromechanical operation thereof when affected by an external stimulus.
Holloway, Nancy M. +4 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Correlation between Composition and Properties of Composite Material Based on Scrap Tires
Purpose of present work is to investigate mechanical and insulation properties of the composite material based on scrap tires and polyurethane-type binder in correlation with composition of composite material. The studies of material’s hardness must be
Mālers, Laimonis +3 more
core
Impact performance of embedded and co-cured composite damping panels
, 2011 The embedded and co-cured composite damping panels comprising of glass fiber layers and one (or more) damping layer(s) embedded into composite material components were designed and manufactured and these are presented in this paper.
Liang, Sen +1 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source