Results 111 to 120 of about 552,574 (312)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Journal of Materials Research and TechnologyRecently, Co–Cr–Ni medium-entropy alloys (MEAs) have garnered significant attention in the materials field owing to exceptional properties. However, the various mechanisms of transformation induced plasticity (TRIP) and twinning induced plasticity (TWIP)
Huicong Dong +6 more
doaj +1 more source
Simulating Postbuckling Behaviour and Collapse of Stiffened CFRP Panels [PDF]
, 2007 Advanced composite materials are well known for their outstanding potential in weight-related stiffness and strength leading to an ever increasing share in aerospace structural components out of Carbon Fibre Reinforced Plastics (CFRP).
Rohwer, Klaus, Degenhardt, Richard
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Thermoelectric and Ignition Effects of Lightning Strikes on Composite–Metal Lap Joints
AerospaceCarbon fiber-reinforced polymer (CFRP) composite–metal joint structures are susceptible to localized discharge and thermal damage under lightning current, posing serious safety concerns for critical aircraft components such as fuel tanks.
Kui Du +5 more
doaj +1 more source
Impact performance of embedded and co-cured composite damping panels [PDF]
, 2011 The embedded and co-cured composite damping panels comprising of glass fiber layers and one (or more) damping layer(s) embedded into composite material components were designed and manufactured and these are presented in this paper.
Liang, Sen +1 more
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Ballistic response mechanism and resistance-driven evaluation method of UHMWPE composite
Defence TechnologyThe use of ultra-high molecular weight polyethylene (UHMWPE) composite in the design of lightweight protective equipment, has gained a lot of interest.
Yemao He +5 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source