Results 71 to 80 of about 549,019 (312)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2010 Traditionally high strain rate material characterisations have been conducted using strain gauges and/or cross head displacements in servo-hydraulic test machines, and force transducers in split Hopkinson bar experiments.
Syngellakis, Stavros +8 more
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Structural Integrity of Functionally Graded Composite Structure using Mindlin-Type Finite Elements. [PDF]
, 2008 In this paper, two new Mindlin-type plate bending elements have been derived for the modelling of functionally graded plate subjected to various loading conditions such as tensile loading, in-plane bending and out-of-plane bending.
Mba, David +2 more
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Composite mechanical properties for use in structural analysis [PDF]
In order to be able to undertake an analysis of a component the designer will need to know the properties of the material being used. The aim of this work is help the design engineer such that the mechanical properties of continuous glass fibre ...
Pinfold, Martyn Keith
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Fibers, 2018 The purpose of this study is to assess the integrity of carbon-fibre reinforced plastics (CFRP) comprising of commercial and surface modified CFs through nanomechanical mapping protocol, towards the feasibility of nanoindentation tool as a quality ...
Elias P. Koumoulos +1 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Effects of aging time on the microstructure and mechanical properties of 18Ni200 maraging steel
Journal of Materials Research and TechnologyThis study investigates the effect of aging treatment on the precipitates and reverse transformed austenite (RTA) in 18Ni200 maraging steel by transmission electron microscopy (TEM), electron backscatter diffraction (EBSD), and X-ray diffraction (XRD ...
Zhibo Yang +7 more
doaj +1 more source