Results 91 to 100 of about 1,533,936 (337)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Armoring Boron Nitride with Pyrolytic Carbon Layers for Tunable Rigidity and Flexibility

Advanced Science
Ceramic aerogels are acclaimed as ideal materials for extreme environments due to their ultrahigh porosity, low density, and exceptional thermal stability.
Meng Lan, Yu Pei, Kexin Huang, Yudong Zhou, Xiao Han, Qiangang Fu   +5 more
doaj   +1 more source

Self-lubricating composite materials [PDF]

The mechanical properties of two types of self lubricating composites (polymer matrix composites and inorganic composites) are discussed.
Sliney, H. E.
core   +1 more source

Controlled intermittent interfacial bond concept for composite materials [PDF]

, 1975
Concept will enhance fracture resistance of high-strength filamentary composite without degrading its tensile strength or elastic modulus. Concept provides more economical composite systems, tailored for specific applications, and composite materials ...
Atkins, A. G., Marston, T. U.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Modelling, Analysis, Fabrication and Experimental Testing of Leaf Spring Material by Hybrid Composite Materials with Natural Fiber for Electric Vehicle

, 2023
Mr. V. Maneesh Babu, G. Prasanthi
openalex   +2 more sources

Strength and toughness of monolithic and composite silicon nitrides [PDF]

The strength and toughness of two composite and two monolithic silicon nitrides were measured from 25 to 1400 C. The monolithic and composite materials were made from similar starting powders.
Salem, Jonathan A.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effects of an enhanced fibre–matrix adhesion on the fatigue behaviour of composite materials under very high cycle fatigue [PDF]

, 2023
Michael Bartelt, Peter Horst, Sebastian Heimbs   +2 more
openalex   +1 more source

Unidirectional composite stiffening [PDF]

, 1970
Simple structural elements are explored with configurations selected to best utilize composite materials. Combination of the biaxial properties of beryllium or an isotropic composite with the uniaxial properties of one directional filamentary ...
Dow, N. F., Rosen, B. W.
core   +1 more source