Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Magnetoelectric Effect in Ni-PZT-Ni Cylindrical Layered Composite Synthesized by Electro-deposition [PDF]
The magnetoelectric (ME) coupling of cylindrical trilayered composite was studied in this paper. The Ni-lead zirconate titanate (PZT)-Ni trilayered cylindrical composite was synthesized by electro-deposition. The maximum ME voltage coefficient of cylindrical ME composite is 35V/cm Oe, about three times higher than that of the plate trilayered composite
arxiv +1 more source
Direct 4D printing via active composite materials
A 4D printing method is developed where the shape of a 3D-printed part can change rapidly into a new permanent one by heating. We describe an approach to print composite polymers in high-resolution three-dimensional (3D) architectures that can be rapidly
Zhen Ding+6 more
semanticscholar +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Chitosan-Based Composite Materials for Prospective Hemostatic Applications
Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis.
Zhang Hu+4 more
semanticscholar +1 more source
Facile preparation of agarose-chitosan hybrid materials and nanocomposite ionogels using an ionic liquid via dissolution, regeneration and sol-gel transition [PDF]
We report simultaneous dissolution of agarose (AG) and chitosan (CH) in varying proportions in an ionic liquid (IL), 1-butyl-3-methylimidazolium chloride [C4mim][Cl].
Kumar, Arvind+2 more
core +2 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Research progress of nitride based ceramic high temperature wave transparent materials
Nitride-based ceramic materials have excellent comprehensive properties such as high strength, high modulus, high temperature resistance, thermal shock resistance and wave-transparent performance.
CUI Xuefeng+7 more
doaj +1 more source
Comprehensive composite materials
A multi-reference source spanning the whole composites science field, this text covers such topics as: fibre reinforcements and general theory of composites; polymer matrix composites; metal matrix composites; test methods, nondestructive evaluation and smart composites; and design and application.
Carl Zweben, Anthony Kelly
openaire +2 more sources