Results 81 to 90 of about 509,261 (302)
Nano-Micro LettersHighlights Developed a versatile HT-based redox polymer electrolyte with exceptional ionic conductivity (73.5 mS cm−1) through self-exchange reaction-based ion hopping mechanism and enhanced polymer chain mobility.
Jeong-Gil Kim +10 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Ablation resistance of C/C-HfC composites
Cailiao gongchengC/C-HfC composites with a density of 2.14 g/cm3 was successfully prepared using an inorganic hafnium solution as a precursor via chemical vapor infiltration (CVI) and precursor infiltration pyrolysis (PIP) methods, and its microstructure and composition ...
ZHENG Peng +5 more
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Intrinsic properties of dispersion-strengthened HfO2–Al2O3–SiO2 material as an EBC bond coat
Journal of Advanced CeramicsTo address the challenges of insufficient thermal resistance and high-temperature stability in current environmental barrier coating (EBC) bond coats above 1500 °C, this study successfully synthesized HfO2–Al2O3–SiO2 powders with a dispersion ...
Deteng Wang +9 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Effect of Hf/Zr ratios on ablation resistance of C/C-HfxZr1-xC composite materials
Cailiao gongchengCarbon/carbon （C/C） composites are prone to oxidation above 370 ℃， which restricts their further utilization in aerospace and military applications. Hence， enhancing the ablation resistance of C/C composites holds paramount significance.
ZHAO Xuning +7 more
doaj +1 more source
THE INFLUENCE OF QUALITY OF CUT SURFACE ON THE STRENGTH CHARACTERISTICS OF PARTS MADE OF COMPOSITE MATERIALS [PDF]
, 2020 Andrei M. Markov +5 more
openalex +1 more source