Results 91 to 100 of about 124,379 (246)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

RESEARCH ON THE MATERIAL CHARACTERISTICS OF WOVEN CARBON FIBER COMPOSITE SQUARE TUBES UNDER THREE-POINT BENDING LOAD (MT)

Jixie qiangdu, 2023
Under the bending load generated by automobile collision, the composite safety components should have the ability to resist deformation and dissipate crashworthiness energy.
CHEN Guang, FENG YuPeng, XIE DongXuan, XIAO Sen, JING GuoXi   +4 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Composite ALPs in Composite Higgs Models

Journal of High Energy Physics
Abstract We study the effective Lagrangian for the Axion-Like Particle (ALP) arising in a class of composite Higgs models. We discuss the peculiarities of the coupling to the quark sector specific of these models, including flavor violating terms. We then confront the main bounds from rare B-meson decays.
openaire   +2 more sources

Compact Compositional Models

, 2014
Learning compact and interpretable representations is a very natural task, which has not been solved satisfactorily even for simple binary datasets. In this paper, we review various ways of composing experts for binary data and argue that competitive forms of interaction are best suited to learn low-dimensional representations.
Goessling, Marc, Amit, Yali
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bubble collapse dynamics near the composite walls: Progress and challenges

Ultrasonics Sonochemistry
Bubble dynamics near the composite walls has become one of the major issues in the fields of aerospace, underwater weapons, and mechanical engineering.
Yichen Zhu, Xiaojian Ma, Ruiquan Zhou, Yuwei Sun, Mindi Zhang   +4 more
doaj   +1 more source

Composite modeling of leaf shape along shoots discriminates Vitis species better than individual leaves. [PDF]

Appl Plant Sci, 2020
Bryson AE, Wilson Brown M, Mullins J, Dong W, Bahmani K, Bornowski N, Chiu C, Engelgau P, Gettings B, Gomezcano F, Gregory LM, Haber AC, Hoh D, Jennings EE, Ji Z, Kaur P, Kenchanmane Raju SK, Long Y, Lotreck SG, Mathieu DT, Ranaweera T, Ritter EJ, Sadohara R, Shrote RZ, Smith KE, Teresi SJ, Venegas J, Wang H, Wilson ML, Tarrant AR, Frank MH, Migicovsky Z, Kumar J, VanBuren R, Londo JP, Chitwood DH.   +35 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An improved composite ship magnetic field model with ellipsoid and magnetic dipole arrays

Scientific Reports
In order to simultaneously maintain the ship magnetic field modeling accuracy, reduce the number of coefficient matrix conditions and the model computational complexity, an improved composite model is designed by introducing the magnetic dipole array ...
Binjie Lu, Xiaobing Zhang
doaj   +1 more source