Results 101 to 110 of about 355,230 (246)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Design of Computer Numerical Control System for Fiber Placement Machine Based on Siemens 840D sl

Sensors
To address the manufacturing demands of large-scale aerospace composite components, this study systematically investigates the coordinated motion characteristics of multi-axis systems in fiber placement equipment.
Kun Xia, Di Zhao, Qingqing Yuan, Jingxia Wang, Aodong Shen   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Interaction of Reggeized Gluons in the Baxter-Sklyanin Representation

, 2001
We investigate the Baxter equation for the Heisenberg spin model corresponding to a generalized BFKL equation describing composite states of n Reggeized gluons in the multi-color limit of QCD.
A.N. Muller, E.A. Kuraev, E.A. Kuraev, E.K. Sklyanin, G.P. Korchemsky, H. J. de Vega, H.J. de Vega, I.S. Gradshteyn, J. Bartels, J. Bartels, J. Bartels, J. Bartels, J. Kwiecinski, J. Wosiek, L. N. Lipatov, L.A. Takhtajan, L.D. Faddeev, L.N. Lipatov, L.N. Lipatov, L.N. Lipatov, L.N. Lipatov, L.N. Lipatov, L.N. Lipatov, L.N. Lipatov, M. Lavrentev, M. Praszalowicz, M.A. Braun, N.N. Lebedev, P. Gauron, P. Gauron, R. Baxter, R. Baxter, R. Baxter, R.A. Janik, V.E. Korepin, V.S. Fadin, Vl.S. Dotsenko, Ya.Ya. Balitsky, Z. Maassarani   +38 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Recent Advances in Conductive Composite Hydrogels for Electronic Skin Applications

Gels
Electronic skins (E-skins) are the integration of intelligent wearable sensors that can collect human physiological, motion, or environmental parameters in real-time through flexible, sensitive materials.
Yiqing Yuan, Yilong Zhang, Haiyang Duan, Yitao Zhang, Lijun Lu, Artem Emel’yanov, Alexander S. Pozdnyakov, Pengcheng Zhu, Yanchao Mao   +8 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Novel Flow Characteristic Regulation Method for Two-Stage Proportional Valves Based on Variable-Gain Feedback Grooves

Machines
The two-stage proportional valve is a key control component in heavy-duty equipment, where its signal-flow characteristics critically influence operational performance.
Xingyu Zhao, Huaide Geng, Long Quan, Chengdu Xu, Bo Wang, Lei Ge   +5 more
doaj   +1 more source

Multipulse Heteroclinic Orbits and Chaotic Dynamics of the Laminated Composite Piezoelectric Rectangular Plate

Discrete Dynamics in Nature and Society, 2013
This paper investigates the multipulse global bifurcations and chaotic dynamics for the nonlinear oscillations of the laminated composite piezoelectric rectangular plate by using an energy phase method in the resonant case.
Minghui Yao, Wei Zhang
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source