Results 81 to 90 of about 566,663 (314)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Recent advances on entropy analysis of composite nanofluids-A critical review

Results in Engineering
The present study analyzes on the reviews carried out by the previous researchers on the entropy generation caused by the flow and heat transfer of several composite nanofluids subject to varieties of geometries under the influence of several constraints
S.S. Samantaray, A. Misra, S. Shaw, M.K. Nayak, S. Nazari, Imed Boukhris, Ali J. Chamkha   +6 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Compositions, Partitions, and Fibonacci Numbers

The Fibonacci Quarterly, 2011
A bijective proof is given for the following theorem: the number of compositions of n into odd parts equals the number of compositions of n + 1 into parts greater than one. Some commentary about the history of partitions and compositions is provided.
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Characteristics of natural convection heat transfer in composite cavity

Case Studies in Thermal Engineering
In order to study the influence of the nature of the mining airspace on the natural convection heat transfer in the unventilated working face, we establish a numerical model of natural convection in a composite cavity containing porous media by CFD ...
Changkui Lei, Yaoqian Zhu, Suntong Qiu, Chengbo Wang, Ruoyu Bao, Cunbao Deng   +5 more
doaj   +1 more source

Relating the total domination number and the annihilation number for quasi-trees and some composite graphs [PDF]

, 2021
Hongbo Hua, Xinying Hua, Sandi Klavžar, Kexiang Xu   +3 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Meteorological indices for potential occurrence of waterspout/tornado in Hong Kong

Meteorologische Zeitschrift
Assessment of the potential occurrence of waterspouts and tornadoes in Hong Kong would be crucial in the timely alerting of these hazardous systems. This system provides for the first time a study of the meteorological parameters that may be useful to ...
Y.T. Leung, K.F. Lam, T.K. Lau, Y.W. Chan, Pak Wai Chan   +4 more
doaj   +1 more source