Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn +20 more
wiley +1 more source
An Atomic-Level Bimetallic MOF Platform Overcoming the Stability-Performance Tradeoff for Laser Propulsion. [PDF]
Rao S, Tang G, Zhang S, Cheng GJ.
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Preparation Technology, Reactivity and Applications of Nano-Aluminum in Explosives and Propellants: A Review. [PDF]
Guo H, Zhang W, Pang W.
europepmc +1 more source
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang +6 more
wiley +1 more source
Preparation of Inverse-Loaded MWCNTs@Fe<sub>2</sub>O<sub>3</sub> Composites and Their Impact on Glycidyl Azide Polymer-Based Energetic Thermoplastic Elastomer. [PDF]
Pang S +5 more
europepmc +1 more source
Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung +7 more
wiley +1 more source
Microstructure and Tensile Properties of Cu-Ti Composites Deposited by Cold Spray Additive Manufacturing. [PDF]
Cheng J +6 more
europepmc +1 more source
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang +15 more
wiley +1 more source
Study on elongation master curve of thermal aging composite modified double base propellant. [PDF]
Zheng J +8 more
europepmc +1 more source

