Results 91 to 100 of about 2,461,830 (355)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
, 2016 In this paper, a new strengthening technique for reinforced concrete (RC) beams is proposed by combining Basalt fiber Reinforced Polymer (BFRP) grid and Engineered Cementitious Composites (ECC) as a composite reinforcement layer (CRL).
Yu-Zhou Zheng, Wenwei Wang, J. Brigham
semanticscholar +1 more source
Designing bioinspired composite reinforcement architectures via 3D magnetic printing
Nature Communications, 2015 Discontinuous fibre composites represent a class of materials that are strong, lightweight and have remarkable fracture toughness. These advantages partially explain the abundance and variety of discontinuous fibre composites that have evolved in the ...
Joshua J. Martin +2 more
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Influence of matrix toughness and interfacial strength on the toughness of epoxy composites with ductile steel fabric reinforcement [PDF]
, 2015 In the last decades, several studies have been performed on polymers reinforced with steel cords or wires. However, the diameter of these steel reinforcements was still quite large (200 micron and more).
Degrieck, Joris +3 more
core +2 more sources
Recent progress of reinforcement materials: a comprehensive overview of composite materials
Journal of Materials Research and Technology, 2019 Emerged in the middle of 20th century, composite materials are now one of the hotspot research topics in the modern technology. Their promising characteristics make them suitable for enormous applications in industrial field such as aerospace, automotive,
D. Rajak +3 more
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Fibreglass Reinforced Composites
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2022 The use of fibreglass products in conservation and available products that can be employed as joints are presented. The experiment relied on comparative tests of load capacity of the dowel joints in wood and fibreglass. The results of this pilot study did not allow to state the advantage of tested fibreglass joints over wood however it opened up the ...
openaire +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Tensile properties of braided composite rods [PDF]
, 2008 The current work is concerning the development of braided reinforced composite rods for civil engineering applications, namely for concrete internal reinforcement.
Araújo, Mário Duarte de +4 more
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