Results 51 to 60 of about 18,459,682 (262)

Governed Fault-Tolerant Quantum Computing on Commodity NISQ Hardware: Surface-Code QEC, Universal FTQC Primitives, FTQC Composition, and Chemical Accuracy FTQC across H2, LiH, H2O, BeH2 Ground States, and the BeH2 Strongly-Multireference Transition State on the IBM Heron r2 and r3 Families of QPUs

Abstract This paper reports the first end-to-end fault-tolerant quantum computing stack to clear all four strict-FTQC requirements simultaneously on commodity superconducting NISQ silicon, rented through standard IBM Quantum cloud subscription with no purpose-built research machine, no custom decoder, and no magic-state distillation factory.
Holt, Denise, Ovseyenko, Denis
openaire   +3 more sources

Augmented Data-Driven Machine Learning for Digital Twin of Stud Shear Connections

Buildings
Existing design codes for predicting the strength of stud shear connections in composite structures are limited when adapting to constant changes in materials and configurations.
Gi-Tae Roh, Nhung Vu, Chi-Ho Jeon, Chang-Su Shim   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Building Codes Agency [PDF]

, 1989
This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government ...

core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Considering the issue of renovating public buildings with reference to in-kind investigations into wall heat transfer coefficients / Visuomeninių pastatų atnaujinimo problemos nagrinėjimas remiantis natūriniais sienų šilumos perdavimo koeficientų tyrimais

Engineering Structures and Technologies, 2013
This article raises the problem of high energy consumption stimulated by heating buildings and preparing hot water. The paper shortly revises the state of renovating public buildings in Lithuania.
Robertas Volvačiovas, Zenonas Turskis, Česlovas Ignatavičius, Leonas Ustinovičius, Audrius Ruzgys   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source