Results 191 to 200 of about 1,552,889 (274)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Study on design optimization of GFRP tubular column composite structure based on machine learning method. [PDF]

PLoS One
Shu P, Xue C, Zhang G, Deng T.
europepmc   +1 more source

Characterizing a Novel Staphylococcal Cassette Chromosome mec with a Composite Structure from a Clinical Strain of Staphylococcus hominis, C34847. [PDF]

Antimicrob Agents Chemother, 2021
McClure JA, Conly JM, Zhang K.
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

The Influence of Variable Stiffness of the Shape Memory Alloys Carbon Composite Structure on Mechanical Vibration. [PDF]

Materials (Basel)
Markuszewski D, Wądołowski M, Krajewski A.   +2 more
europepmc   +1 more source

Mechanical Performance Test and Numerical Simulation Analysis of Building Steel Plate and Concrete Composite Structure.

Int J Anal Chem, 2022
Liu Q.
europepmc   +1 more source

Application of PZT Ceramic Sensors for Composite Structure Monitoring Using Harmonic Excitation Signals and Bayesian Classification Approach. [PDF]

Materials (Basel), 2021
Dziendzikowski M, Heesch M, Gorski J, Dragan K, Dworakowski Z.   +4 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Numerical Simulation Study on Impact Initiation on Shielded Charge Using Hypervelocity Composite-Structure Reactive Fragments. [PDF]

Polymers (Basel)
Lu Y, Tan B, Li Y, Tan S, Yang S, Ji W.
europepmc   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source