Results 71 to 80 of about 371,806 (260)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Bioinspired Double‐Broadband Switchable Microwave Absorbing Grid Structures with Inflatable Kresling Origami Actuators

Advanced Science
Tunable radar stealth structures are critical components for future military equipment because of their potential to further enhance the design space and performance.
Zhong Zhang, Hongshuai Lei, Shengyu Duan, Zeang Zhao, Mingji Chen, Changxian Wang, Daining Fang   +6 more
doaj   +1 more source

Long-term oxidation of Ti3Al0.8Sn0.2C2 in air at 1200 °C

Open Ceramics
The addition of Sn into the raw materials is currently one of the most widely used methods to improve the purity and mechanical properties of Ti3AlC2. It follows in this work to investigate the oxidation behavior of the resulting Ti3Al0.8Sn0.2C2 at 1200 °
Hang Yin, Xiaodong He, Kebin Qin, Guangping Song, Yongting Zheng, Yuelei Bai   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Analysis of impact damage mechanisms in aeronautical Cf/SiC composites via molecular dynamics simulation [PDF]

AIP Advances
To investigate the damage mechanisms of composite and monolithic materials under diamond shot impact, this study employs molecular dynamics simulations to construct models of diamond-tipped projectiles impacting Cf/SiC composites and pure carbon fiber ...
Yulin Ouyang, Xuezhou Luo, Chenggui Liao, Weiwen Hu, Jiao Li, Zengguang Lai   +5 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The structure response of sandwich beams with metallic auxetic honeycomb cores under localized impulsive loading-experiments and finite element analysis

Materials & Design, 2019
In recent years, auxetic cellular materials such as auxetic reentrant honeycombs were widely studied due to its attractively negative Poisson's ratio.
Dengbao Xiao, Xiaoqi Chen, Ying Li, Wenwang Wu, Daining Fang   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Estimation of the Wind Load Required to Cause the Overturning of a Gantry Crane, Comparing Different Structures of the Main Horizontal Girder

Applied Sciences
The present paper concerns the problem of estimating the loading induced by the wind on a gantry crane standing in the open air. Sufficiently strong wind may cause the device to move or even tip over. Two different structures were studied, namely the box
Marcin Augustyn, Marek Barski
doaj   +1 more source