Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Geographical Variation of Diet Composition of <i>Cervus nippon kopschi</i> in Jiangxi, China Based on DNA Metabarcoding. [PDF]
Sun X+7 more
europepmc +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
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Exploring Bird Gut Microbiota Through Opportunistic Fecal Sampling: Ecological and Evolutionary Perspectives. [PDF]
Fablet L+4 more
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Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
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Learning tissue representation by identification of persistent local patterns in spatial omics data. [PDF]
Tanevski J+5 more
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Composition, purification, and certain constants of ammonia
E. C. McKelvy, C. S. Taylor
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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Determining trichome elemental composition in Solanum wild and domesticated species using SEM-EDS. [PDF]
Ojo FM+5 more
europepmc +1 more source
XIII.—On the composition and analysis of black ash or ball soda [PDF]
J. W. Kynaston
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