Results 241 to 250 of about 3,840,908 (313)

CT-based body composition and its change through time in relation to outcomes in participants screened for lung cancer. [PDF]

EBioMedicine
Bunk S, Bennink E, Sidorenkov G, Heuvelmans MA, Groen HJM, Gietema HA, Prokop M, Aerts JG, Jacobs C, de Bock GH, de Jong PA, Vliegenthart R, Mohamed Hoesein F, NELSON-POP consortium.   +13 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Bidirectional regulation of gut microbiota and young ruminant host: implications for intestinal development and mucosal immunity. [PDF]

J Anim Sci Biotechnol
Walelegne M, Junnan M, Hao Y, Feng X, Abebe H, Yang R, Kong L, Tu Y.   +7 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Substrate Protein Enrichment of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae for Diets of Olive Flounder (<i>Paralichthys olivaceus</i>). [PDF]

Aquac Nutr
Jeong SM, Min BH, Bae J, Kim M, Hur SW, Park K, Kim KW.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Association Between Phase Angle, Muscle Mass Distribution, and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease. [PDF]

J Clin Med
Ibrayeva L, Bacheva I, Sadibekova M.
europepmc   +1 more source

Concert: Composition Studio Recital

, 2017
Composition Studio
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

AI-Based Imaging Assessment of Body Composition in Oncology: A Step Toward Routine Clinical Practice Integration. [PDF]

Healthcare (Basel)
Mattavelli E, Cotogni P, Caccialanza R.
europepmc   +1 more source