Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Effects of Supplementation of Chlorella vulgaris Biomass on Egg Production and Composition of Laying Hens. [PDF]
Jonova S +9 more
europepmc +1 more source
Modeling strength and ductility of alloys with intragrain compositional inhomogeneities
A. V. Smirnov +3 more
openalex +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Association between apolipoprotein E gene polymorphisms and the effects of high-intensity interval training on body composition in university students. [PDF]
Chu HN +6 more
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Physical function, physical activity, muscle strength, and body composition: Clinical practice recommendations in pediatric intestinal failure and transplantation-position statement of the International Intestinal Rehabilitation and Transplant Association Allied Health Committee. [PDF]
Patterson C +9 more
europepmc +1 more source

