Results 71 to 80 of about 1,309,267 (345)

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Visões da língua(gem) em comentários sobre internetês não é língua portuguesa

open access: yesFilologia e Linguística Portuguesa, 2006
This paper aims to discuss the representation that university students of letters and pedagogy courses use in the so-called “internetês”, a grapholinguistic form which has been spread in digital genres such as chats, blogs and social networks as the ...
Fabiana Komesu
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

PECULIARITIES OF THE MUSICAL LANGUAGE, COMPOSITION AND DRAMATURGY IN S. PISLARI’S COMPOSITION LES CANTILÈNES FOR PIANO [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2017
The author of the given article analyzes the piano work by Snejana Pislari «Les Cantilènes», considered from the aspect of content and form. The conclusion is made that the musical language and the specifics of the composition and dramaturgy of this work
CABACOV DMITRII, ŢIRCUNOVA SVETLANA
doaj  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Transit Manipulation by the Koch Brothers: Analyzing the Relationship between the Division of Power in the United States Government, Societal Benefits, Voter and Rider Composition, Referendum Language and Cost of Improvement Under the Lens of the 2018 Nashville Transit Improvement Program Referendum [PDF]

open access: yes, 2020
Transit Manipulation by the Koch Brothers: Analyzing the Relationship between the Division of Power in the United States Government, Societal Benefits, Voter and Rider Composition, Referendum Language and Cost of Improvement Under the Lens of the 2018 ...
Lee, Samantha
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Can creative writing in Latin support students' confidence in and enjoyment of A Level prose composition?

open access: yesThe Journal of Classics Teaching
This research aims to explore the ways in which creative writing may be used as a pedagogical tool in the Latin language classroom, in particular how creative writing may benefit students in Latin prose composition.
Emily Romain
doaj   +1 more source

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