Results 81 to 90 of about 389,674 (277)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Weighted Composition Operators and Supercyclicity Criterion

International Journal of Mathematics and Mathematical Sciences, 2011
We consider an equivalent condition to the property of Supercyclicity Criterion, and then we investigate this property for the adjoint of weighted composition operators acting on Hilbert spaces of analytic functions.
Bahmann Yousefi, Javad Izadi
doaj   +1 more source

Kitai's Criterion for composition operators

Journal of Mathematical Analysis and Applications
We present a general and natural framework to study the dynamics of composition operators on spaces of measurable functions, in which we then reconsider the characterizations for hypercyclic and mixing composition operators obtained by Bayart, Darji and Pires.
Daniel Gomes, Karl-G. Grosse-Erdmann
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Continuous Frames Under the Weighted Composition Operators on the Weighted Bergman Space

Axioms
We investigate the behavior of continuous frames in the weighted Bergman space Aα2 over the unit disc under the action of weighted composition operators. Motivated by developments in the discrete frame setting, we provide a comprehensive characterization
Fatma Bozkurt, Faruk Yilmaz
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A new class of composition operators

International Journal of Mathematics and Mathematical Sciences, 1987
A new class of composition operators Pϕ:H2(T)→H2(T), with ϕ:T→D¯ is introduced. Sufficient conditions on ϕ for Pϕ to be bounded and Hilbert-Schmidt are obtained.
S. Pattanayak, C. K. Mohapatra, A. K. Mishra   +2 more
doaj   +1 more source

ORDER BOUNDED WEIGHTED COMPOSITION OPERATORS [PDF]

Journal of the Australian Mathematical Society, 2012
AbstractLet$\phi $and$\psi $be analytic maps on the open unit disk$D$such that$\phi (D) \subset D$. Such maps induce a weighted composition operator$C_{\phi ,\psi }$acting on weighted Banach spaces of type$H^{\infty }$or on weighted Bergman spaces, respectively. We study when such operators are order bounded.
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source