Results 81 to 90 of about 391,009 (282)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Isometric and Closed-Range Composition Operators between Bloch-Type Spaces
International Journal of Mathematics and Mathematical Sciences, 2011 We present an overview of the known results describing the isometric and closed-range composition operators on different types of holomorphic function spaces.
Nina Zorboska
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Composition operators acting on weighted Hilbert spaces of analytic functions [PDF]
Sahand Communications in Mathematical Analysis, 2015 In this paper, we considered composition operators on weighted Hilbert spaces of analytic functions and observed that a formula for the essential norm, gives a Hilbert-Schmidt characterization and characterizes the membership in Schatten-class for ...
Mostafa Hassanlou
doaj
Isometries and spectra of multiplication operators on the Bloch space
, 2008 In this paper, we establish bounds on the norm of multiplication operators on the Bloch space of the unit disk via weighted composition operators. In doing so, we characterize the isometric multiplication operators to be precisely those induced by ...
Allen, Robert F., Colonna, Flavia
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Aluthge transforms of unbounded weighted composition operators in $L^2$-spaces
, 2018 We describe the Aluthge transform of an unbounded weighted composition operator acting in an $L^2$-space. We show that its closure is also a weighted composition operator with the same symbol and a modified weight function.
Benhida, Chafiq +2 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source