Results 91 to 100 of about 7,066 (291)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Team Automata Satisfying Compositionality
, 2003 . A team automaton is said to satisfy compositionality if its behaviour can be described in terms of the behaviour of its constituting component automata.
Maurice H. Ter Beek, Jetty Kleijn
core +1 more source
Why Rationalist Compositionality Won't Go Away (Either)
Theoria, 2009 Vigorous Fodorian criticism may make it seem impossible for Inferential Role Semantics (IRS) to accommodate compositionality. In this paper, first, I introduce a neo-Fregean version of IRS that appeals centrally to the notion of rationality.
Víctor M. Verdejo
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Compositionality in the language of emotion
PLOS ONE, 2018 Emotions are signaled by complex arrays of face and body actions. The main point of contention in contemporary treatments is whether these arrays are discrete, holistic constellations reflecting emotion categories, or whether they are compositional-comprised of smaller components, each of which contributes some aspect of emotion to the complex whole ...
Cavicchio F. +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Communication and the Complexity of Semantics
, 2012 I first argue that we have reason to look to the computational needs of communication for justifying the claim that natural language semantics is compositional. I then turn to discussing appropriate measures of computa- tional complexity. For the measure
Pagin, Peter, Pagin, Peter,
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Determinate compositionality [PDF]
First-order logic is obviously compositional. However, given standard syntactic and semantic assumptions, first-order logic does not count as compositional by the standard definition.
Trueman, Robert
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source