Results 71 to 80 of about 7,066 (291)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Polysemy in Compositional Distributional Semantics [PDF]
, 2012 Research in distributional semantics has made good progress in capturing individual word meanings using contextual frequencies obtained from a large corpus.
Reddy, Siva
core
This is a preprint of an extended version of https://doi.org/10.1007/978-3-031-71261-6_3 Formal Aspects of Component Software. FACS 2024. Lecture Notes in Computer Science, vol 15189. pp 39-56. This extended version adds new sections about combining the different introduced algorithms and how to apply them in practice, as well as several new examples ...
Cuyck, G. van +2 more
openaire +4 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Compositionality in Kaplan style semantics
, 2012 I investigate how the notion of compisitionality can be adapted to various kinds of semantics that take context dependence seriously.
Westerståhl, Dag,
core +1 more source
Studies in Logic, Grammar and Rhetoric, 2015 The paper concentrates on the problem of adequate reflection of fragments of reality via expressions of language and inter-subjective knowledge about these fragments, called here, in brief, language adequacy. This problem is formulated in several aspects,
Wybraniec-Skardowska Urszula
doaj +1 more source
LingBaW, 2019 The developments in Cognitive Linguistics have made it possible to uncover multiple meanings of composite structures to the effect that more and more scholars have become interested in the issue of semantic relations in verb-particle constructions. With
Izabela Jarosz
doaj +1 more source