Results 51 to 60 of about 7,066 (291)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Compositionality : the open-access journal for the mathematics of composition
, 2019 core +5 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Body as Evidence for the Nature of Language
Frontiers in Psychology, 2018 Taking its cue from sign languages, this paper proposes that the recruitment and composition of body actions provide evidence for key properties of language and its emergence. Adopting the view that compositionality is the fundamental organizing property
Wendy Sandler
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2019 This note presents a presheaf theoretic approach to the construction of fuzzy sets, which builds on Barr\u27s description of fuzzy sets as sheaves of monomorphisms on a locale.
John F. Jardine, Jardine, J. F.
core +1 more source
The meaning and development of the Hebrew scalar modifier kexol
Topics in Linguistics, 2018 The purpose of this paper is twofold; first, it aims to explore the variety of interpretations of the partially schematic Hebrew construction kexol as in kexol she’ratsiti (‘as much as I wanted’) within the framework of construction grammar; second, it ...
Shefer Hagit
doaj +1 more source
Microbiome Multi-Omics Network Analysis: Statistical Considerations, Limitations, and Opportunities
Frontiers in Genetics, 2019 The advent of large-scale microbiome studies affords newfound analytical opportunities to understand how these communities of microbes operate and relate to their environment.
Duo Jiang +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source