Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Donor gettering of InGaAsP layers grown by liquid-phase epitaxy in the presence of Er
, 2012 [[fileno]]2030154030023[[department ...
Y. M. Lin;E. H. Chen;C. M. Chiu;M. C. Wu;Y. K. Tu
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
An Analysis Of Compound Words On Culinary Terms In Masterchef U.S. Season 7 (2016)
, 2016 This research focuses on the process of compound words used on the food terms in MasterChef US Season 7 (2016). This qualitative descriptive research is aimed in describing the types and the meaning of compound words. To analyze the compound word process,
Denise Sheilla Noumianty
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Artist residency at The Compound 13 Lab: Part of the AHRC funded Rethinking Waste Project
, 2020 Compound 13 Lab is a space for experimental design and learning. Our programme introduces design and media tools, audiovisual technologies, 3D design and digital fabrication to disadvantaged, marginalised citizens who because of their socio-economic ...
Graham, Jeffrey, Dawson, Ian, Parry, Ben
core
Optimization of Cost-properties in Production of a General Purpose Conveyer Belt Using Taguchi Method with Overall Evaluation Criteria Method [PDF]
علوم و تکنولوژی پلیمر, 2005 A. Ramazani, Z. Kamakani
doaj +1 more source
1380 nm VCSELs using surface-activated bonding of GaAs-based DBRs on a Ge substrate
Applied Physics ExpressA wafer-bonded vertical-cavity surface-emitting laser (VCSEL) was demonstrated by surface-activated bonding (SAB) of a GaAs-based distributed Bragg reflector (DBR) on a Ge substrate.
Tomomasa Watanabe +8 more
doaj +1 more source