Results 91 to 100 of about 31,094 (285)

Multi-domain vibration dataset with various bearing types under compound machine fault scenarios

Data in Brief
In modern complex mechanical systems, machine faults typically occur in multiple components simultaneously, and the domain of collected sensor data changes continuously due to variations in operating conditions.
Seongjae Lee, Taewan Kim, Taehyoun Kim
doaj   +1 more source

Photovoltaic Array Fault Diagnosis Based on Gaussian Kernel Fuzzy C-Means Clustering Algorithm

Sensors, 2019
In the fault diagnosis process of a photovoltaic (PV) array, it is difficult to discriminate single faults and compound faults with similar signatures. Furthermore, the data collected in the actual field experiment also contains strong noise, which leads
Shengyang Liu, Lei Dong, Xiaozhong Liao, Xiaodong Cao, Xiaoxiao Wang   +4 more
doaj   +1 more source

AI Solutions for MDS: Artificial Intelligence Techniques for Misuse Detection and Localisation in Telecommunication Environments [PDF]

, 2006
This report considers the application of Articial Intelligence (AI) techniques to the problem of misuse detection and misuse localisation within telecommunications environments.
Anyakoha, Chukwudi, Bauerdick, H., Gottfried, B., Mintram, Robert, Muthuraman, S., Phalp, Keith T., Vincent, Jonathan   +6 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Isolation and Identification of Compound Faults in Rotating Machinery via Adaptive Deep Filtering Technique

IEEE Access, 2019
Compound defects commonly occur on rotating machinery under fatigue and heavy loads, and their fault signatures are coupled and easily buried in strong unwanted vibrations and background noise.
Chunlin Zhang, Yuling Liu, Fangyi Wan, Binqiang Chen, Jie Liu   +4 more
doaj   +1 more source

Expert systems for real-time monitoring and fault diagnosis [PDF]

Methods for building real-time onboard expert systems were investigated, and the use of expert systems technology was demonstrated in improving the performance of current real-time onboard monitoring and fault diagnosis applications.
Caglayan, A. K., Edwards, S. J.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The Absolute Deviation Rank Diagnostic Approach to Gear Tooth Composite Fault

Shock and Vibration, 2017
Aiming at nonlinear and nonstationary characteristics of the different degree with single fault gear tooth broken, pitting, and composite fault gear tooth broken-pitting, a method for the diagnosis of absolute deviation of gear faults is presented.
Guangbin Wang, Wenhui Deng, Xiaoyang Du, Xuejun Li   +3 more
doaj   +1 more source