Results 71 to 80 of about 3,123 (260)

A Rail Fault Diagnosis Method Based on Quartic C² Hermite Improved Empirical Mode Decomposition Algorithm

Sensors, 2019
For compound fault detection of high-speed rail vibration signals, which presents a difficult problem, an early fault diagnosis method of an improved empirical mode decomposition (EMD) algorithm based on quartic C2 Hermite interpolation is presented ...
Hanzhong Liu, Chaoxuan Qin, Ming Liu
doaj   +1 more source

Improved DCNN Based on Multi-Source Signals for Motor Compound Fault Diagnosis

, 2022
Induction motors, the key equipment for rotating machinery, are prone to compound faults, such as a broken rotor bars and bearing defects. It is difficult to extract fault features and identify faults from a single signal because multiple fault features ...
Xiaoyun Gong, Tao Wang, Wenliao Du, Zeheng Zhi, Kunpeng Feng   +4 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A multitask-aided transfer learning-based diagnostic framework for bearings under inconsistent working conditions. [PDF]

, 2020
Rolling element bearings are a vital part of rotating machines and their sudden failure can result in huge economic losses as well as physical causalities. Popular bearing fault diagnosis techniques include statistical feature analysis of time, frequency,
Kim, Jong-Myon, Hasan, Md. Junayed, Jong-Myon Kim, Md Junayed Hasan, Sohaib, Muhammad, Muhammad Sohaib   +5 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The correlation analysis of gear tooth broken-pitting compound fault and single fault based on Laplacian Eigenmaps [PDF]

, 2018
Gear break and pitting are two common faults in transmission system, when these two faults coexist and form a compound fault, the damage speed and frequency of gear transmission system will be greatly increased.
Guangbin Wang, Long Li, Xiaoyang Du, Wenhui Deng, Yinghang He   +4 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A Diagnosis Method for the Compound Fault of Gearboxes Based on Multi-Feature and BP-AdaBoost

, 2020
Gearbox is an important structure of rotating machinery, and the accurate fault diagnosis of gearboxes is of great significance for ensuring efficient and safe operation of rotating machinery.
Aqiang Lin, Weiyi Wu, Zhonghua Cheng, Xiaobo Su, Yunxian Jia, Yangyang Zhang   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source