Results 61 to 70 of about 3,123 (260)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Compact convolutional transformers- generative adversarial network for compound fault diagnosis of industrial robot [PDF]
The safe operation of Industrial robots is a major concern in intelligent manufacturing. Accurate compound fault diagnosis is essential to the safe operation of industrial robots, while it is challenging to achieve since the compound fault samples are ...
Chen, Chong +4 more
core +1 more source
Compound fault diagnosis for a rolling bearing using adaptive DTCWPT with higher order spectra
, 2020 Fault diagnosis plays a vital role in prognostics and health management. Researchers have devoted their efforts in enhancing the accuracy of fault diagnosis. However, diagnosis of compound faults in complex systems is still a challenging task.
Shao, Haidong +7 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Adaptive resonance demodulation semantic-induced zero-shot compound fault diagnosis for railway bearings [PDF]
For the challenges of diverse compound faults and low identification accuracy of railway bearings, a new zero-shot diagnosis model based on adaptive resonance demodulation semantic is proposed for the compound fault diagnosis of railway bearings.
Gu, Fengshou +5 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
SensorsTo address the problem that complex bearing faults are coupled to each other, and the difficulty of diagnosis increases, an improved envelope spectrum–maximum second-order cyclostationary blind deconvolution (IES-CYCBD) method is proposed to realize the ...
Fengxia He +9 more
doaj +1 more source