Results 61 to 70 of about 31,713 (311)

Getting the Haves to Come out Behind: Fixing the Distributive Injustices of American Health Care [PDF]

, 2006
Hyman criticizes an article by Havighurst and Richman regarding the distributive injustices of US health care.
Hyman, David A.
core   +4 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Application of improved FastICA algorithm in compound fault diagnosis of vibrating scree

Gong-kuang zidonghua, 2017
In view of problem that common fault characteristic extraction methods could not extract compound fault characteristic completely and effectively, an improved fast independent component analysis(FastICA) algorithm was proposed.
XU Yuanbo, CAI Zongyan
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Detection and Diagnosis of Compound Faults in Induction Motors Using Electric Signals from Variable Speed Drives [PDF]

, 2016
As a primer driver, induction motors are the most electric energy consuming component in industry. The exposure of the motor to stator winding asymmetry, combined with broken rotor bar fault significantly increases the temperature and reduces the ...
Ball, Andrew, Gu, Fengshou, Haba, Usama, Lane, Mark, Shaeboub, Abdulkarim   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An Imbalanced Fault Diagnosis Method Based on TFFO and CNN for Rotating Machinery

Sensors, 2022
Deep learning-based fault diagnosis usually requires a rich supply of data, but fault samples are scarce in practice, posing a considerable challenge for existing diagnosis approaches to achieve highly accurate fault detection in real applications.
Long Zhang, Yangyuan Liu, Jianmin Zhou, Muxu Luo, Shengxin Pu, Xiaotong Yang   +5 more
doaj   +1 more source

Towards the text compression based feature extraction in high impedance fault detection [PDF]

, 2019
High impedance faults of medium voltage overhead lines with covered conductors can be identified by the presence of partial discharges. Despite it is a subject of research for more than 60 years, online partial discharges detection is always a challenge,
Fulneček, Jan, Hrbáč, Roman, Mišák, Stanislav, Prílepok, Michal, Vantuch, Tomáš   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source