Results 51 to 60 of about 3,279,297 (229)

Transnosis: Transformer-Variation-based Bearing Compound Fault Diagnosis with Zero-shot Learning and Domain Adaptation

Engineered Science
Bearing compound fault diagnosis is an important problem, and signal data from the target bearing are collected and inputted into deep learning model for diagnosis.
Qi Liu, Wenjing Liu, Chao Peng, Yuming Fan, Biao Wang, Hang Zhang, Ergude Bao, Jiqiang Liu   +7 more
doaj   +1 more source

Application of improved FastICA algorithm in compound fault diagnosis of vibrating scree

Gong-kuang zidonghua, 2017
In view of problem that common fault characteristic extraction methods could not extract compound fault characteristic completely and effectively, an improved fast independent component analysis(FastICA) algorithm was proposed.
XU Yuanbo, CAI Zongyan
doaj   +1 more source

Compound Fault Diagnosis Method of Modular Multilevel Converter Based on Improved Capsule Network

IEEE Access, 2022
When submodule (SM) compound fault occurs in the Modular multilevel converter (MMC), the time-domain waveform characteristics of output current and internal circuiting current of MMC are not obvious, especially on the condition of high-level MMC.
Longzhang Ke, Yi Liu, Yi Yang
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Two Stage Helical Gearbox Fault Detection and Diagnosis based on Continuous Wavelet Transformation of Time Synchronous Averaged Vibration Signals [PDF]

, 2012
Vibration signals from a gearbox are usually very noisy which makes it difficult to find reliable symptoms of a fault in a multistage gearbox. This paper explores the use of time synchronous average (TSA) to suppress the noise and Continue Wavelet ...
Gu, Fengshou, Ball, Andrew, Zhen, Dong, Wang, T., Gu, F., Zhen, D., Elbarghathi, F., Elbarghathi, Fathalla, Ball, A.   +8 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Thermal Image Enhancement using Bi-dimensional Empirical Mode Decomposition in Combination with Relevance Vector Machine for Rotating Machinery Fault Diagnosis [PDF]

, 2009
In this study, a novel fault diagnosis system for rotating machinery using thermal imaging is proposed. This system consists of bi-dimensional empirical mode decomposition (BEMD) for image enhancement, a generalized discriminant analysis (GDA) for ...
Yang, Bo-Suk, Gu, Fengshou, Ball, Andrew, Al-Ani, A, Yang, Bo Suk, Tran, Van Tung, Al-Jumaily, A, Khushaba, RN   +7 more
core   +1 more source