Results 91 to 100 of about 3,123 (260)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The harmonic modulation bispectrum:a modulated vibration signal analysis method for compound fault diagnosis of gearboxes [PDF]

In the compound fault diagnosis of gearboxes based on vibration signal, the fault feature information often exists in the complex modulation components of the signal.
Gu, Fengshou, Hu, Aijun, Xu, Yonggang, Yang, Miaorui, Zhang, Kun   +4 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

A high-precision fault diagnosis method for photovoltaic arrays considering the effect of missing data

Frontiers in Electronics
With the increasing penetration of photovoltaic (PV) systems into power grids, the accurate diagnosis of PV array health has become critical for ensuring the stable operation of power systems.
Di Liu, Xiaojuan Zhu, Changyu Du
doaj   +1 more source

The Absolute Deviation Rank Diagnostic Approach to Gear Tooth Composite Fault

Shock and Vibration, 2017
Aiming at nonlinear and nonstationary characteristics of the different degree with single fault gear tooth broken, pitting, and composite fault gear tooth broken-pitting, a method for the diagnosis of absolute deviation of gear faults is presented.
Guangbin Wang, Wenhui Deng, Xiaoyang Du, Xuejun Li   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Intelligent Diagnosis of Compound Faults of Gearboxes Based on Periodical Group Sparse Model

Applied Sciences
A gearbox compound fault intelligent diagnosis method based on the period group sparse model is proposed for the problem that the fault features are coupled with each other and the fault components are superimposed on each other and difficult to be ...
Lan Chen, Xiangfeng Zhang, Lizhong Wang, Kaihua Li, Yang Feng   +4 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Diagnosis of Compound Fault Using Sparsity Promoted-Based Sparse Component Analysis

Sensors, 2017
Compound faults often occur in rotating machinery, which increases the difficulty of fault diagnosis. In this case, blind source separation, which usually includes independent component analysis (ICA) and sparse component analysis (SCA), was proposed to ...
Yansong Hao, Liuyang Song, Yanliang Ke, Huaqing Wang, Peng Chen   +4 more
doaj   +1 more source