Results 61 to 70 of about 939,391 (232)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mechanism–Data Fusion Modeling and Cross-Condition Fault Diagnosis of Typical Faults in Marine Solid Oxide Fuel Cell Power Systems

Journal of Marine Science and Engineering
Solid oxide fuel cell (SOFC) systems in shipboard power plants exhibit strong thermal–electrochemical coupling and are highly sensitive to both balance-of-plant and stack-related faults under changing operating conditions. In this study, a mechanism–data
Guoqiang Liu, Xuelei Chen, Jingxuan Peng, Xiaolong Wu, Zhengyang Long   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Automatic March tests generation for static and dynamic faults in SRAMs [PDF]

, 2005
New memory production modern technologies introduce new classes of faults usually referred to as dynamic memory faults. Although some hand-made March tests to deal with these new faults have been published, the problem of automatically generate March ...
Di Natale, Giorgio, Bosio, Alberto, A. Benso, P. Prinetto, A. Bosio, G. Di Natale, Benso, Alfredo, Prinetto, Paolo Ernesto, S. Di Carlo, Di Carlo, Stefano   +9 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Transnosis: Transformer-Variation-based Bearing Compound Fault Diagnosis with Zero-shot Learning and Domain Adaptation

Engineered Science
Bearing compound fault diagnosis is an important problem, and signal data from the target bearing are collected and inputted into deep learning model for diagnosis.
Qi Liu, Wenjing Liu, Chao Peng, Yuming Fan, Biao Wang, Hang Zhang, Ergude Bao, Jiqiang Liu   +7 more
doaj   +1 more source

Diagnosis of Compound Fault Using Sparsity Promoted-Based Sparse Component Analysis

Sensors, 2017
Compound faults often occur in rotating machinery, which increases the difficulty of fault diagnosis. In this case, blind source separation, which usually includes independent component analysis (ICA) and sparse component analysis (SCA), was proposed to ...
Yansong Hao, Liuyang Song, Yanliang Ke, Huaqing Wang, Peng Chen   +4 more
doaj   +1 more source

Research on the Fault Diagnosis Method for Rolling Bearings Based on Improved VMD and Automatic IMF Acquisition

Shock and Vibration, 2020
This paper proposes a novel method to improve the variational mode decomposition (VMD) method and to automatically acquire the sensitive intrinsic mode function (IMF).
Ying Zhang, Anchen Wang
doaj   +1 more source