Results 81 to 90 of about 4,524,731 (322)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Unconventional magnetism in the 4d$^{4}$ based ($S=1$) honeycomb system Ag$_{3}$LiRu$_{2}$O$_{6}$

, 2019
We have investigated the thermodynamic and local magnetic properties of the Mott insulating system Ag$_{3}$LiRu$_{2}$O$_{6}$ containing Ru$^{4+}$ (4$d$$^{4}$) for novel magnetism.
Baines, C., Büttgen, N., Chakraborty, Atasi, Dasgupta, I., Dey, Tusharkanti, Ette, P. M., Gegenwart, P., Gippius, A. A., Kumar, R., Kundu, S., Mahajan, A. V., Orain, J. C., Prinz-Zwick, M., Ramesha, K., Shahee, A., Tóth, Sándor   +15 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Multi-domain vibration dataset with various bearing types under compound machine fault scenarios

Data in Brief
In modern complex mechanical systems, machine faults typically occur in multiple components simultaneously, and the domain of collected sensor data changes continuously due to variations in operating conditions.
Seongjae Lee, Taewan Kim, Taehyoun Kim
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Compound hydrocarbon accumulation and enrichment in southwestern Huizhou Sag, Pearl River Mouth Basin, South China Sea

Petroleum Exploration and Development, 2015
Aimed at four major issues in the oil and gas exploration of the southwestern Huizhou area in Pearl River Mouth Basin, in-depth study on geologic features and oil and gas reservoir forming pattern has been carried out to find out the exploration ...
Weitao CHEN, Jiayuan DU, Hesheng SHI, Min HE   +3 more
doaj   +1 more source

MintHint: Automated Synthesis of Repair Hints

, 2013
Being able to automatically repair programs is an extremely challenging task. In this paper, we present MintHint, a novel technique for program repair that is a departure from most of today's approaches. Instead of trying to fully automate program repair,
Cadar C., Chandola V., Cramér H., Groce A., Jin G., Kendall M., Konighofer R., Vessey I.   +7 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Mechanism–Data Fusion Modeling and Cross-Condition Fault Diagnosis of Typical Faults in Marine Solid Oxide Fuel Cell Power Systems

Journal of Marine Science and Engineering
Solid oxide fuel cell (SOFC) systems in shipboard power plants exhibit strong thermal–electrochemical coupling and are highly sensitive to both balance-of-plant and stack-related faults under changing operating conditions. In this study, a mechanism–data
Guoqiang Liu, Xuelei Chen, Jingxuan Peng, Xiaolong Wu, Zhengyang Long   +4 more
doaj   +1 more source

Annealing-induced enhancement of ferromagnetism and nano-particle formation in ferromagnetic-semiconductor GeFe

, 2014
We report the annealing-induced enhancement of ferromagnetism and nano-particle formation in group-IV-based ferromagnetic-semiconductor GeFe. We successfully increase the Curie temperature of the Ge0.895Fe0.105 film up to ~220 K while keeping a single ...
Ban, Yoshisuke, Ohya, Shinobu, Tanaka, Masaaki, Wakabayashi, Yuki   +3 more
core   +1 more source