Results 161 to 170 of about 2,923,525 (317)

Selenium-Containing 1,4-Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple-Negative Breast Cancer Cells. [PDF]

Drug Dev Res
Angulo-Elizari E, Raza A, Johnson H, Martínez-Sáez N, Encío I, Sharma AK, Sanmartín C, Plano D.   +7 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Merkmal(s?)analyse, Seminar(s?)arbeit und Essen(s?)ausgabe: Zweifelsfälle der Verfugung als Indikatoren für Sprachwandel

Zeitschrift für Sprachwissenschaft, 2011
Nübling Damaris, Szczepaniak Renata
doaj   +1 more source

Fast and Sensitive Measurement of Off-Flavors in Recirculating Aquaculture Systems. [PDF]

Rapid Commun Mass Spectrom
Noguera PM, Holt S, Podduturi R, Bredie WLP, Beauchamp JD, Petersen MA.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Protein-enhanced small molecule disruptors of ordered membrane domains. [PDF]

Proc Natl Acad Sci U S A
Stefanski KM, Li GC, Luu DD, Fosu KK, Guadarrama E, Hutchison JM, Saksena N, Zuy Y, Fisch AJ, Hasaka TP, Bauer JA, George AL, Kenworthy AK, Horn WDV, Sanders CR.   +14 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

New class of photochromic heterocyclic compounds

, 2000
Base catalyzed condensation of fulgide (7) with compounds containing active methylene groups such as (8a - 8d) has yielded new class of photo chromatic compounds 3-Dicyclopropylmethylene-4-E-[I-(2,5- dimethyl- 3-furyl)ethylidene)- 5-(4 ...
Al-Shihry, Shar S.
core  

Comparative lipidomics and volatile profiling reveal distinct aroma signatures in Arbas cashmere goat meat from grazing and housed feeding systems. [PDF]

J Anim Sci Biotechnol
Zhang C, Du X, Fan D, Zhang J, Wang A, Song Z, Zhong P, Bai R, Diao Q, Zhang N.   +9 more
europepmc   +1 more source