Results 91 to 100 of about 286,909 (314)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Baseline concentration levels of trace elements as a function of clay and organic carbon contents in soils in Flanders (Belgium) [PDF]
, 1997 A
Tack, Filip +3 more
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
EFSA JournalFollowing a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the efficacy of copper(II)‐betaine complex as a nutritional feed additive for ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +19 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Application of Neurospora crassa in the Treatment of Waste [PDF]
, 2014 The nutrient requirements of the fast growing filamentous fungi Neurospora crassa to convert animal waste into an edible product containing high amounts of protein were assessed by selectively excluding nutrients from supplemental solutions of Vogel ...
Przybyla, Matthew, Wunderlich, John
core +1 more source
Arsenic-bearing phases in South Andean volcanic ashes: Implications for As mobility in aquatic environments [PDF]
, 2015 Three samples of volcanic ashes collected after eruptions of the volcanos Hudson in 1991, Chaitén in 2008 and Puyehue in 2011 were analyzed in order to define the solid speciation of arsenic and the dynamics of its release to the aqueous phase.
Bia, Gonzalo Luis +3 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Procedure to use phosphogypsum industrial waste for mineral CO 2 sequestration [PDF]
, 2011 Industrial wet phosphoric acid production in Huelva (SW Spain) has led to the controversial stockpiling of waste phosphogypsum by-products, resulting in the release of significant quantities of toxic impurities in salt marshes in the Tinto river estuary.
Cárdenas Escudero, Cristian +4 more
core +1 more source