Results 141 to 150 of about 31,094 (313)
This paper considers the transfer of approaches from the field of to the field of to be used in decision support systems. The most relevant of the developed approaches will be roughly introduced and it will be considered how these approaches can be ...
Apeldoorn, Daan
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A narrative review on do’s and don’ts in prescription label writing – lessons for pharmacists
Nithushi R Samaranayake,1 Wasana GRSK Bandara,2 Chinthana MGA Manchanayake2 1Department of Allied Health Sciences, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka; 2Colombo South Teaching Hospital, Kalubowila, Dehiwala,
Samaranayake NR +2 more
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We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The comprehensibility of scientific experts is fundamentally important but presents a challenge for experts and their audiences. The definition and evaluation of comprehensibility are central to developing approaches for improvement.
Monika Taddicken, Claudia Thoms
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Assessing the Cognitive Sign Features and Guessability of Laboratory Safety Signs for Pharmacy Students [PDF]
Background and Purpose: Correct recognition of hazards in academic labs by using safety signs can prevent injuries in these settings. Although safety signs seem simple, misunderstanding them can put students at risk.
Hajiomid Kalteh +4 more
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