Results 111 to 120 of about 2,718,187 (290)

Wandel im Gesundheitswesen: Analyse der Auswirkungen auf Ärzte und Patienten am Beispiel der Ukraine [PDF]

open access: yes, 2020
Background The health care sector is experiencing a drastic transition all over the world. This has an impact not only on the way hospitals, clinics, special-care homes etc.
Bogodistov, Yevgen   +3 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Integralidade na perspectiva de enfermeiros da Estratégia Saúde da Família

open access: yesRevista Bioética
Resumo Este estudo objetivou conhecer a percepção de enfermeiros sobre a integralidade do ser humano na prática do cuidado de enfermagem no contexto da Estratégia Saúde da Família.
Fabiana da Penha Colimoide   +3 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The Challenge of Comprehensive Health Care

open access: yesAmerican Journal of Public Health and the Nations Health, 1962
COMPREHENSIVE health care is a cherished goal for the American people. It constitutes a challenge to both the consumers and the providers of medical care. Before analyzing this challenge, however, it is prudent to consider what we mean by this broad, popular term. The Articles of Incorporation of the Group Health Association of America use it. Yet, our
openaire   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Understanding the development and implementation of national quality of care and patient safety strategic documents: a scoping review

open access: yesBMC Health Services Research
Background Several strategic documents aimed at integrating quality of care and patient safety into health systems have been developed, both as guiding documents produced by renowned international organisations and as national documents with a political ...
Maria Mafalda Fernandes   +9 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Health (including Clinical Studies) [PDF]

open access: yes
Politics, science, research and the public base their discussions on comprehensive, valid and systematic health care data. Data based information is needed in order to measure the results or success of a policy of procedure.
Bertram Häussler, Elke Hempel
core  

Rationale, design and conduct of a comprehensive evaluation of a primary care based intervention to improve the quality of life of osteoarthritis patients. The PraxArt-project: a cluster randomized controlled trial [ISRCTN87252339] ; study protocol [PDF]

open access: yes, 2005
Background: Osteoarthritis (OA) has a high prevalence in primary care. Conservative, guideline orientated approaches aiming at improving pain treatment and increasing physical activity, have been proven to be effective in several contexts outside the ...
Gensichen, Jochen   +6 more
core  

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