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Quantification of ADHD Medication in Biological Fluids with Liquid Chromatography: A Comprehensive Review - Metadata

<p>This file is the metadata related to the publication "Quantification of ADHD Medication in Biological Fluids with Liquid Chromatography: A Comprehensive Review".</p ...
De Hondt, Lena
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effect of pharmacist-led medication reviews on appropriateness of prescribing in patients with dementia – results from the cluster randomized controlled “DemStepCare” study

BMC Geriatrics
Background Patients with dementia (PwD) are often geriatric patients treated with multimedication increasing the risk of drug-related problems (DRP) and inappropriate prescriptions.
Marie Kocklaeuner, Katharina Geschke, Andreas Fellgiebel, Irene Kraemer   +3 more
doaj   +1 more source

‘You would rather not fill your body with pills’—patient perspectives on polypharmacy and medication reviews by pharmacists in general practice

Scandinavian Journal of Primary Health Care
Introduction Polypharmacy is widespread. The demographic shift toward older patients receiving multiple medications increases risk and drug-related problems in these patients.Objective To investigate patient perspectives on polypharmacy and the ...
Josefine Graabæk Als, Janus Laust Thomsen, Sabrina Storgaard Sørensen, Søren Paaske Johnsen, Camilla Hoffmann Merrild   +4 more
doaj   +1 more source

Potentially Inappropriate Medication: A Pilot Study in Institutionalized Older Adults

Institutionalized older adults often face complex medication regimens, increasing their risk of adverse drug events due to polypharmacy, overprescribing, medication interactions, or the use of Potentially Inappropriate Medications (PIM). However, data on
Helena Leitão, Ezequiel Pinto, Cabrita, Catarina, Tânia Nascimento, Nascimento, Tânia, Pinto, Ezequiel, Leitao, Helena, Amanda Andrade, Catarina Cabrita, Andrade, Amanda de Oliveira   +9 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Medication adherence in the elderly: A comprehensive review

National Journal of Pharmacology and Therapeutics
Medication adherence is critical for managing chronic diseases, especially among the elderly, who often face multiple comorbidities and polypharmacy. This review explores the multifaceted nature of medication adherence in the elderly, including definitions, the importance of adherence, factors affecting adherence, and strategies to improve it.
Shambo Samrat Samajdar, Rohan Tripathi, Shravan Venkatraman, Shatavisa Mukherjee, Jyotirmoy Pal, Santanu Kumar Tripathi, Shashank R Joshi, Anuj Maheshwari   +7 more
openaire   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Feasibility of a comprehensive medication review to improve medication use for patients with cancer and comorbid conditions. [PDF]

Support Care Cancer, 2022
Mackler ER, Azar MK, Johengen E, Farris KB, Thompson AN.   +4 more
europepmc   +1 more source