Results 81 to 90 of about 16,504,620 (285)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sleep Quality and Medication Adherence in Older Adults: A Systematic Review
Clocks & SleepSleep quality significantly impacts individuals’ overall health, especially in older adults. Older adults often face comorbid conditions, polypharmacy (the intake of five or more medications per day), and medication non-adherence, which are common among ...
Leandro Amato +10 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Impact of a community pharmacist-led medication review on medicines use in patients on polypharmacy - a prospective randomised controlled trial [PDF]
, 2016 In 2010 the 'Polymedication Check' (PMC), a pharmacist-led medication review, was newly introduced to be delivered independently from the prescriber and reimbursed by the Swiss health insurances.
Vriends, Noortje +15 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Optimizing care transitions: the role of the community pharmacist [Corrigendum]
Integrated Pharmacy Research and Practice, 2019 Melody KT, McCartney E, Sen S, Duenas G. Integr Pharm Res Pract. 2016;5:43–51.The authors on this paper have advised us that they were contacted by one of the authors of reference number 40 notifying them that the author list for this ...
Melody KT, McCartney E, Sen S, Duenas G
doaj
Tackling polypharmacy in geriatric patients: Is increasing physicians’ awareness adequate?
Archives of Gerontology and Geriatrics PlusPolypharmacy among geriatric patients poses significant clinical and economic challenges, including increased risks of adverse drug reactions, cognitive decline, and hospitalizations.
Henry Sutanto
doaj +1 more source
Medical Expert System- A Comprehensive Review
International Journal of Computer Applications, 2015 Diseases must be treated healthy and on time. If they are not treated lying on time, they can escort to many health problems with these problems might become the reason of death. These problems are becoming inferior due to the scarcity of specialists, health facilities and practitioners.
openaire +1 more source
Medication administration errors for older people in long-term residential care [PDF]
, 2011 Background Older people in long-term residential care are at increased risk of medication errors. The purpose of this study was to evaluate a computerised barcode medication management system designed to improve drug administrations in residential and ...
Nelson Sara +12 more
core +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source