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Parallel comprehensive two-dimensional gas chromatography

Journal of Chromatography A, 2017
We introduce an information rich analytical approach called parallel comprehensive two-dimensional gas chromatography (2GC×2GC). This parallel chromatography approach splits injected samples into two independent two-dimensional column ensembles and provides two GC×GC separations by using contra-directional thermal modulation.
DanDan, Yan   +4 more
openaire   +2 more sources

Comprehensive two-dimensional gas chromatography in metabolomics

Analytical and Bioanalytical Chemistry, 2012
One of the major objectives in metabolomics is the identification of subtle changes in metabolite profiles as affected by genetic or environmental factors. Comprehensive two-dimensional gas chromatography (GC × GC) hyphenated to a fast-acquisition mass spectrometer is a well-established analytical technique to study the composition of complex samples ...
Martin F, Almstetter   +2 more
openaire   +2 more sources

Comprehensive two-dimensional gas chromatography

Analytical and Bioanalytical Chemistry, 2003
This chapter will present an overview of the comprehensive two-dimensional gas chromatography (GC×GC) technique, and in particular, in the context of considering the second dimension column separation as a monitor or analysis step subsequent to the first dimension.
Danielle, Ryan, Philip, Marriott
openaire   +3 more sources

Modulation Ratio in Comprehensive Two-dimensional Gas Chromatography

Analytical Chemistry, 2006
Comprehensive two-dimensional chromatography employs a serially coupled two-column arrangement where effluent from the first column is collected or sampled and then introduced to the second column according to a chosen modulation period. This is effected by use of a modulator at or near the column junction.
Weeraya, Khummueng   +2 more
openaire   +2 more sources

Comprehensive Two-dimensional Gas Chromatography

2019
This chapter contains information related to the use of comprehensive two-dimensional gas chromatography (GC×GC) for the analysis of compounds contained in food products. General principles, basic theory and practical issues, along with instrumental features, are reported. In particular, and apart from other forms of detection, the use of various forms
Tranchida P. Q., Mondello L.
openaire   +2 more sources

Orthogonality considerations in comprehensive two-dimensional gas chromatography

Journal of Chromatography A, 2005
This study explores separation orthogonality with respect to comprehensive two-dimensional gas chromatography (GC x GC) for a range of different column polarities in the first dimension (1D), with two second dimension (2D) column types. Systematic variation in the net polarity of the first dimension allows the effect of column phase relative polarity ...
Danielle, Ryan   +2 more
openaire   +2 more sources

Modulators for comprehensive two-dimensional gas chromatography

TrAC - Trends in Analytical Chemistry, 2011
Abstract The analytical benefits of comprehensive two-dimensional gas chromatography (GC × GC) methods have been exploited and emphasized in the past two decades. The unexpectedly complex nature of many real-world samples amenable to GC analysis has been elucidated through the enhanced resolving power of GC × GC.
Peter Q Tranchida   +2 more
exaly   +3 more sources

Detector technologies for comprehensive two‐dimensional gas chromatography

Journal of Separation Science, 2006
AbstractThe detector is an integral and important part of any chromatographic system. The chromatographic peak profiles (i. e. peak separation) should, ideally, be unaffected by the detector – it should only provide the sensing capacity required at the end of a column separation process.
Carin, von Mühlen   +4 more
openaire   +2 more sources

Retention indices in comprehensive two-dimensional gas chromatography

Analytical and Bioanalytical Chemistry, 2011
The identification of compounds by using gas chromatography (GC) in samples with significant complexity comprising a range of isomeric species, where characterization is based on peak retention times and mass spectra, generates uncertainty for the analyst. This leads to identification errors.
Carin, von Mühlen, Philip J, Marriott
openaire   +2 more sources

Comprehensive Two-Dimensional Gas Chromatography with Fast Enantioseparation

Analytical Chemistry, 2002
The development of fast chiral analysis for use in comprehensive two-dimensional gas chromatography in which a short second dimension enantioselective capillary column provides a route to precise measurement of chiral ratios of enantiomers is described.
Robert, Shellie, Philip J, Marriott
openaire   +2 more sources

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