Results 241 to 250 of about 8,130,325 (342)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Leadership practices and maternal and child health outcomes in Sub-Saharan Africa: a systematic review. [PDF]

BMC Health Serv Res
Mayeden SY, Hoffmann I, Chit M, Posti JP, Wilson ML, Louis VR, Marx M, Koku Awoonor-Wiliams J, Yawson AE, Horstick O, Deckert A, Dambach P.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Does dosage matter? Effects of results-based financing layered on top of less comprehensive direct facility financing in Tanzania. [PDF]

Health Policy Plan
Loha E, Somville V, Borghi J, Binyaruka P, Mæstad O.   +4 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Embedding a primary care provider in sickle cell teams improves sickle cell care. [PDF]

PLoS One
Della-Moretta S, Li Welkie R, Quaye N, Landes K, Crawford RD, Desai P, Cronin RM.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Mapping Speech-Language Pathology and Audiology Rehabilitation Services Across Saudi Arabia: A Retrospective Cross-Sectional Study. [PDF]

Audiol Res
Alharbi MF, Alanazi AA.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Timing of specialist palliative care and acute healthcare utilization at the end of life among adults who died of cancer: a nationwide cohort study. [PDF]

BMC Cancer
Nåhls NS, Lehto HR, Ahtiluoto S, Nuutinen M, Finne-Soveri H, Saarto T, Carpén T.   +6 more
europepmc   +1 more source