Results 41 to 50 of about 385,409 (264)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Initial pyrolysis mechanism and product formation of cellulose: An Experimental and Density functional theory(DFT) study

open access: yesScientific Reports, 2020
In this paper, analytical pyrolyzer coupled with a gas chromatography–mass spectrometry set-up (Py-GC/MS) and density functional theory(DFT) theory was used to reveal the initial pyrolysis mechanism and product formation mechanism of cellulose pyrolysis.
Qing Wang   +5 more
doaj   +1 more source

Recovery of Ilmenite from an Ultrafine Fine Particle Material in Panxi

open access: yesKuangchan zonghe liyong, 2023
This is an essay in the field of mineral processing engineering. This study conducted a test study on the recovery of Ilmenite from an Ultrafine Fine Particle Material in Panxi, determined the overall process flow of strong magnetic preconcentration ...
Jian Deng   +4 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Distribution State of Zinc and the Rare Elements Gallium and Germanium in a Zinc Ore

open access: yesKuangchan zonghe liyong
This is an article in the field of process mineralogy. The occurrence of zinc, associated dispersed elements Ga and Ge and the distribution characteristics of the main carrier minerals of a zinc ore in China are studied in detail by means of chemical ...
Lili ZHANG   +5 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Effect of Deformation Process on Mechanical Properties of Hot-Extruded Mg-Y-Zn-Gd-Zr-Ca Alloy

open access: yesCrystals
Mg–Y–Zn alloys have attracted considerable attention for lightweight structural applications; however, the influence of extrusion temperature on microstructural evolution and the underlying mechanisms governing strength–ductility synergy remains ...
He Guo   +7 more
doaj   +1 more source

Development of a Pure Certified Reference Material of D-Mannitol

open access: yesMolecules, 2023
A new certified reference material (CRM) of D-mannitol (GBW(E) 100681) has been developed in this study. We describe the preparation, structure determination, characterization, homogeneity study, stability study, as well as uncertainty estimation.
Weizhu Chen   +8 more
doaj   +1 more source

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