Results 61 to 70 of about 385,409 (264)

The complete chloroplast genome sequence of Sinojackia huangmeiensis (Styracaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2020
Sinojackia huangmeiensis J. W. Ge & X. H. Yao is a member of the genus Sinojackia endemic to central and east China. Here we assembled and annotated the complete chloroplast (cp) genome.
Hongjin Dong   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Characterization of Viral Communities and Two Novel Viruses in Symptomatic Tea Plants via Ribodepleted Transcriptome Sequencing

open access: yesInternational Journal of Plant Biology
The tea plant (Camellia sinensis (L.) O. Kuntze) is a globally important crop, yet its cultivation is continually challenged by a range of viral pathogens that can compromise plant health and product quality.
Rongrong Tan   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Ultrasound Utility in the Management of Morphea: A Comprehensive Review

open access: yesIndian Dermatology Online Journal
Abstract Introduction: Morphea, an autoimmune progressive disorder, can significantly impact patient well-being, yet therapeutic options, though expanding, exhibit limited efficacy. A persistent challenge in disease management revolves around monitoring disease activity and gauging treatment effectiveness.
Raza Khan, Amor Khachemoune
openaire   +3 more sources

Study on Calcified Alkali Leaching of Vanadium-Extracted Tailings and Preparation of Barium Orthovanadate

open access: yesNanomaterials
While vanadium-extracted tailings contain valuable components, their utilization is difficult due to their high sodium content. In this work, a new oxygen-pressure calcification and alkaline leaching strategy to achieve barium orthovanadate vanadium ...
Jinwei Qu, Yiqiu Wang, Xinyu Hao, Na Ma
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy